Keywords Borderline tumours, conservative treatment, fertility, ovary, recurrence, stromal microinvasion. Please cite this paper as: Laurent I, Uzan C, Gouy S, Pautier P, Duvillard P, Morice P. Results after conservative treatment of serous borderline tumours of the ovary with stromal microinvasion but without micropapillary pattern.
Hums PATROL 21:397-403. Objective The aims of this study were to evaluate the rate of recurrences in borderline ovarian tumors (BOTs) with microinvasion and to evaluate the possibility to enlarge fertility-sparing surgery in this group of patients. Two of 13 (15%, 95% CI 8.7, 21.3) patients with microinvasion died of recurrent invasive cancer, whereas only 1 out of 113 patients without microinvasion died of recurrent borderline tumor (OR 20 The nomenclature and diagnostic criteria of mucinous borderline ovarian tumors (M-BOTs) are controversial. We report a case of M-BOT with microinvasion that relapsed, with an unfavorable outcome.
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2007-07-01 · Microinvasion was easily identified in SBT by a change in architecture (Fig. 4, Fig. 5). There was a higher epithelial to stromal ratio than the adjacent serous borderline tumor. The microinvasive tumors were composed of one or more single cells, small nests and small papillae in desmoplastic stroma.
All 3 patients with an aggressive disease course and poor outcome had increasing CA 125 levels at the time of recurrence. Comments: Borderline clear cell adenofibroma with a 2mm focus of microinvasion in a 10 cm tumor.
Introduction: Taylor first described borderline ovarian tumors (BOTs) in 1929. The most frequent subtypes are serous and mucinous BOTs. The 2014 WHO Classification of Tumors of Female Reproductive Organs established as histopathological features of BOTs: microinvasion, micropapillary pattern, noninvasive implants and linfonodal invasion in serous BOTs as well as microinvasion,
tema gynekologisk cancer: 50 KI-professorer bakom medicinpriset AKTUELLT. Home · Målriktad behandling ett Clinical significance of microinvasion in borderline ovarian tumors and its impact on surgical management Although exploratory, our data suggest that BOTs with microinvasion present earlier relapses, but overall incidence of relapses and overall survival do not differ significantly from BOTs without microinvasion. Microinvasion, invasive implants and recurrences all showed qualitative histologic resemblance to carcinoma.
endometrioid tumours and the seropapillary low grade/borderline tumours showed intermediate sensitivity. In contrast, docetaxel showed the opposite pattern
Borderline ovarian tumor. Borderline ovarian tumours differ from epithelial ovarian cancer by their low incidence, frequent association with infertility, low association with mutations in BCRA genes, different percentages of the most common histological types, early stage diagnosis, and high survival rate, even when associated with peritoneal involvement.
These data suggest that serous borderline tumors with microinvasion have a prognosis similar to that of the usual serous borderline tumor, and that conservation of the contralateral ovary and uterus may be acceptable therapy in young women who wish to preserve their fertility. Hums PATROL 21:397-403.
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The qualitative histologic similarity between microinvasion, invasive implants, recurrences and grade 1 serous carcinoma suggests that microinvasion represents early invasion and is not just another histologic pattern of SBT. These data suggest that serous borderline tumors with microinvasion have a prognosis similar to that of the usual serous borderline tumor, and that conservation of the contralateral ovary and uterus may be acceptable therapy in young women who wish to preserve their fertility.
D. Chamberlin et al., 2001; M. B. …
Borderline tumors account for 14 to 15 percent of all primary ovarian neoplasms .
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Borderline tumors account for 14 to 15 percent of all primary ovarian neoplasms . Borderline tumors occur in a variety of histologies, as in epithelial ovarian carcinoma . The majority of cases are serous or mucinous. Rarely, endometrioid, clear-cell, or transitional cell (Brenner) borderline tumors are found.
The. Borderline Resectable and Locally Advanced Pancreas Cancer: FDG PET/MRI and CT Tumor Metrics for Assessment of Neoadjuvant Therapy Pathologic Regionala cancercentrum i samverkan 2015-06-04 peritonealcancer och epiteliala borderlinetumörer i ovariet with microinvasion.